BIOL4397 - Evolution of Development

 Lecture 4 - Canalization & Evolvability

Lecture Notes [pdf]   (Note: Updated version.)

Slides [pdf]

Required Reading

  • Rutherford SL & Lindquist S (1998) Hsp90 as a capacitor for morphological evolution. Nature 396: 336-42. [pdf]

Recommended Reading
  • de Visser JAGM, et al. (2003) Evolution and detection of genetic robustness. Evolution 57: 1959-72. [pdf]

  • Queitsch C, et al. (2002) Hsp90 as a capacitor for phenotypic variation. Nature 417: 618-24. [pdf]

  • Wagner GP, et al. (1999) Is Hsp90 a regulator of evolvability? Mol. Dev. Evol. 285: 116-18. [pdf]

  • Wagner GP & Altenberg L (1996) Complex adaptations and the evolution of evolvability. Evolution 50: 967-76. [pdf]